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SMPD1 抗体 (C-Term)

SMPD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31029 unconjugated
产品编号 ABIN656161
发货至: 中国
  • 抗原 See all SMPD1 抗体
    SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
    抗原表位
    • 15
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 391-419, C-Term
    适用
    • 49
    • 25
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 42
    • 6
    • 1
    克隆类型
    • 43
    • 6
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMPD1 antibody is un-conjugated
    应用范围
    • 41
    • 21
    • 18
    • 13
    • 13
    • 12
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SMPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1.
    克隆位点
    RB31029
    亚型
    IgG
  • 应用备注
    WB: 1:2000. WB: 1:4000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500. FC: 1:25
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    SMPD1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • Ullio, Casas, Brunk, Sala, Fabriàs, Ghidoni, Bonelli, Baccino, Autelli: "Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).

  • 抗原
    SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
    别名
    SMPD1 (SMPD1 产品)
    别名
    ASM antibody, ASMASE antibody, NPD antibody, A-SMase antibody, Zn-SMase antibody, aSMase antibody, SMPD1 antibody, sphingomyelin phosphodiesterase 1 antibody, sphingomyelin phosphodiesterase 1, acid lysosomal antibody, sphingomyelin phosphodiesterase antibody, SMPD1 antibody, Smpd1 antibody, LOC5578088 antibody
    背景
    The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
    分子量
    69936
    基因ID
    6609
    NCBI登录号
    NP_000534, NP_001007594
    UniProt
    P17405
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