SMPD1 抗体 (C-Term)
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- 抗原 See all SMPD1 抗体
- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
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抗原表位
- AA 391-419, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMPD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SMPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1.
- 克隆位点
- RB31029
- 亚型
- IgG
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- 应用备注
- WB: 1:2000. WB: 1:4000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- SMPD1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).
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Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).
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- 抗原
- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
- 别名
- SMPD1 (SMPD1 产品)
- 别名
- ASM antibody, ASMASE antibody, NPD antibody, A-SMase antibody, Zn-SMase antibody, aSMase antibody, SMPD1 antibody, sphingomyelin phosphodiesterase 1 antibody, sphingomyelin phosphodiesterase 1, acid lysosomal antibody, sphingomyelin phosphodiesterase antibody, SMPD1 antibody, Smpd1 antibody, LOC5578088 antibody
- 背景
- The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
- 分子量
- 69936
- 基因ID
- 6609
- NCBI登录号
- NP_000534, NP_001007594
- UniProt
- P17405
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