p130 抗体 (N-Term)
(1 reference)-
- 抗原 See all p130 (RBL2) 抗体
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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抗原表位
- AA 165-194, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This p130 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 预测反应
- M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This RBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the N-terminal region of human RBL2.
- 克隆位点
- RB31021
- 亚型
- Ig Fraction
- Top Product
- Discover our top product RBL2 Primary Antibody
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibody
RBL2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2C8A8 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 大鼠, 小鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 878-913) antibodyRBL2 适用: 人, 大鼠 WB, IF, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal 130P215 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 100-200) antibodyRBL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4D7 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (C-Term) antibodyRBL2 适用: 人, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000. FC: 1:10~50. FC: 1:25
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- RBL2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- 有效期
- 6 months
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: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).
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: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).
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- 抗原
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- 别名
- RBL2 (RBL2 产品)
- 别名
- RBL2 antibody, RBR2 antibody, RRB2a antibody, PRB2 antibody, RBR-2 antibody, Rb2 antibody, p130 antibody, P130 antibody, retinoblastoma-like 2 (p130) antibody, RB transcriptional corepressor like 2 antibody, related to retinoblastoma 2 antibody, RBL2 antibody, LOC541652 antibody, Rbl2 antibody
- 背景
- RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. RBL2 may act as a tumor suppressor.
- 分子量
- 128367
- 基因ID
- 5934
- NCBI登录号
- NP_005602
- UniProt
- Q08999
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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