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PPARD 抗体 (C-Term)

PPARD 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31677 unconjugated
产品编号 ABIN655880
发货至: 中国
  • 抗原 See all PPARD 抗体
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    抗原表位
    • 16
    • 12
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 367-394, C-Term
    适用
    • 79
    • 29
    • 20
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 76
    • 10
    • 1
    克隆类型
    • 78
    • 9
    多克隆
    标记
    • 43
    • 10
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPARD antibody is un-conjugated
    应用范围
    • 77
    • 40
    • 27
    • 16
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PPARD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-394 amino acids from the C-terminal region of human PPARD.
    克隆位点
    RB31677
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPARD Primary Antibody
  • 应用备注
    WB: 1:1000. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PPARD (Peroxisome Proliferator-Activated Receptor delta (PPARD))
    别名
    PPARD (PPARD 产品)
    别名
    FAAR antibody, NR1C2 antibody, NUC1 antibody, NUCI antibody, NUCII antibody, PPARB antibody, NUC-1 antibody, Nr1c2 antibody, PPAR-beta antibody, PPAR-delta antibody, PPAR[b] antibody, PPARdelta antibody, Pparb antibody, Pparb/d antibody, PPARBETA antibody, ppard antibody, pparb antibody, PPARD antibody, PPAR-D/B antibody, peroxisome proliferator activated receptor delta antibody, peroxisome proliferator activator receptor delta antibody, peroxisome proliferator activated receptor delta S homeolog antibody, peroxisome proliferator-activated receptor delta antibody, PPARD antibody, Ppard antibody, ppard.S antibody, ppard antibody
    背景
    This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants.
    分子量
    49903
    基因ID
    5467
    NCBI登录号
    NP_001165289, NP_001165290, NP_001165291, NP_006229, NP_803184
    UniProt
    Q03181
    途径
    Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Monocarboxylic Acid Catabolic Process, Smooth Muscle Cell Migration, Positive Regulation of fat Cell Differentiation
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