RGD1306411 antibody, si:ch211-79l17.3 antibody, WT1 interacting protein antibody, Wilms tumor 1 interacting protein antibody, WT1 interacting protein L homeolog antibody, WT1-interacting protein antibody, Wtip antibody, WTIP antibody, wtip antibody, wtip.L antibody
背景
WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).