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Nibrin 抗体 (C-Term)

Name: Nibrin 抗体 (C-Term)
SKU: ABIN655721
Availability: OutOfStock

NBN 适用: 人 WB, IF, FACS 宿主: 兔 Polyclonal RB19072 unconjugated

NBN Antibody (C-term) (ABIN655721 and ABIN2845169) western blot analysis in NCI-,NCI- cell line lysates (35 μg/lane). (Nibrin 抗体 (C-Term))

NBN Antibody (C-term) (ABIN655721 and ABIN2845169) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control cell (left histogram). (Nibrin 抗体 (C-Term))

FACS

Confocal immunofluorescent analysis of NBN Antibody (C-term) (ABIN655721 and ABIN2845169) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). (Nibrin 抗体 (C-Term))

3 images

产品编号 ABIN655721

发货至: 中国

Datasheet as PDF

抗原 See all Nibrin (NBN) 抗体

Nibrin (NBN)
抗原表位
37

15

11

7

7

5

5

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 602-630, C-Term
适用
100

60

36

2

1

1

1

1
人
宿主
117

15
兔
Compatible Secondaries
克隆类型
108

24
多克隆
标记
66

8

5

4

4

4

4

4

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2
This Nibrin antibody is un-conjugated
应用范围
103

47

27

27

26

26

23

16

9

8

6

4

2

2

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This NBN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 602-630 amino acids from the C-terminal region of human NBN.

克隆位点

RB19072

亚型

Ig Fraction

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anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

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NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

Nibrin (NBN)

别名

NBN (NBN 产品)

别名

NBN antibody, AT-V1 antibody, AT-V2 antibody, ATV antibody, NBS antibody, NBS1 antibody, P95 antibody, Nbs1 antibody, im:6911679 antibody, zgc:194152 antibody, nibrin antibody, NBN antibody, nbn antibody, Nbn antibody

背景

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

分子量

84959

基因ID

4683

NCBI登录号

NP_002476

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response