COCH 抗体 (C-Term)
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- 抗原 See all COCH 抗体
- COCH (Cochlin (COCH))
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抗原表位
- AA 492-520, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COCH antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human COCH.
- 克隆位点
- RB20929
- 亚型
- Ig Fraction
- Top Product
- Discover our top product COCH Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- COCH (Cochlin (COCH))
- 别名
- COCH (COCH 产品)
- 别名
- AW122937 antibody, Coch-5B2 antibody, D12H14S564E antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody, cochlin antibody, Coch antibody, COCH antibody
- 背景
- The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].
- 分子量
- 59483
- 基因ID
- 1690
- NCBI登录号
- NP_001128530, NP_004077
- UniProt
- O43405
- 途径
- Sensory Perception of Sound
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