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FZD6 抗体 (AA 493-520)

FZD6 适用: 人 WB 宿主: 兔 Polyclonal RB25725 unconjugated
产品编号 ABIN654962
发货至: 中国
  • 抗原 See all FZD6 抗体
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    抗原表位
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 493-520
    适用
    • 36
    • 13
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 36
    • 2
    • 2
    • 1
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 28
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FZD6 antibody is un-conjugated
    应用范围
    • 25
    • 17
    • 7
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This FZD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 493-520 amino acids from the Central region of human FZD6.
    克隆位点
    RB25725
    亚型
    Ig Fraction
    Top Product
    Discover our top product FZD6 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    FZD6 (Frizzled Family Receptor 6 (FZD6))
    别名
    FZD6 (FZD6 产品)
    别名
    zgc:65879 antibody, zgc:77440 antibody, fz6 antibody, frz6 antibody, Xfrz6 antibody, frizzled6 antibody, frizzled-6 antibody, FZ-6 antibody, FZ6 antibody, HFZ6 antibody, NDNC10 antibody, Frizzled-6 antibody, Fz6 antibody, frizzled class receptor 6 antibody, frizzled class receptor 6 S homeolog antibody, fzd6 antibody, fzd6.S antibody, FZD6 antibody, Fzd6 antibody
    背景
    This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
    分子量
    79292
    基因ID
    8323
    NCBI登录号
    NP_001158087, NP_001158088, NP_003497
    UniProt
    O60353
    途径
    WNT signaling, Tube Formation
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