CASP5 抗体 (AA 162-191)
Quick Overview for CASP5 抗体 (AA 162-191) (ABIN654898)
抗原
See all CASP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 162-191
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CASP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human CASP5.
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亚型
- Ig Fraction
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anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 145-327) antibody
CASP5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 162-191) antibodyCASP5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) antibodyCASP5 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 146-175), (Middle Region) antibodyCASP5 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) antibodyCASP5 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Cleaved-Ser331) antibodyCASP5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Cleaved-Asp121) antibodyCASP5 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (AA 251-300) antibodyCASP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Middle Region) antibodyCASP5 适用: 人, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5) (Intermediate Domain) antibodyCASP5 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))
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别名
- CASP5
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背景
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
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分子量
- 49736
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基因ID
- 838
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NCBI登录号
- NP_001129581, NP_001129582, NP_001129584, NP_004338
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UniProt
- P51878
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途径
- Inflammasome
抗原
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