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FBXW8 抗体 (AA 270-299)

FBXW8 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28550 unconjugated
产品编号 ABIN654676
发货至: 中国
  • 抗原 See all FBXW8 抗体
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    抗原表位
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 270-299
    适用
    • 20
    • 16
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 34
    • 1
    克隆类型
    • 35
    多克隆
    标记
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXW8 antibody is un-conjugated
    应用范围
    • 34
    • 17
    • 13
    • 13
    • 13
    • 11
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This FBXW8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of human FBXW8.
    克隆位点
    RB28550
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Wang, Chen, Lin, Li, Zhou, Liu, Logsdon, Jin, Abbruzzese, Tan, Wang: "The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1." in: The Journal of biological chemistry, Vol. 289, Issue 7, pp. 4009-17, (2014) (PubMed).

  • 抗原
    FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))
    别名
    FBXW8 (FBXW8 产品)
    别名
    FBW6 antibody, FBW8 antibody, FBX29 antibody, FBXO29 antibody, FBXW6 antibody, 4930438M06Rik antibody, Fbx29 antibody, F-box and WD repeat domain containing 8 antibody, ring finger protein, transmembrane 2 antibody, F-box and WD-40 domain protein 8 antibody, FBXW8 antibody, Fbxw8 antibody, RNFT2 antibody
    背景
    This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
    分子量
    67394
    基因ID
    26259
    NCBI登录号
    NP_036306, NP_699179
    UniProt
    Q8N3Y1
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