COX10 抗体 (C-Term)
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- 抗原 See all COX10 抗体
- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
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抗原表位
- AA 383-410, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COX10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This COX10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-410 amino acids from the C-terminal region of human COX10.
- 克隆位点
- RB24307
- 亚型
- Ig Fraction
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anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (Middle Region) antibody
COX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 386-414), (C-Term) antibodyCOX10 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) antibodyCOX10 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-443) antibodyCOX10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 215-264) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 180-229) antibodyCOX10 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome C Oxidase Assembly Homolog 10 (COX10) (AA 1-160) antibodyCOX10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))
- 别名
- COX10 (COX10 产品)
- 别名
- 2410004F01Rik antibody, AU042636 antibody, im:7145568 antibody, im:7157205 antibody, wu:fb18a03 antibody, F4I1.50 antibody, F4I1_50 antibody, cytochrome c oxidase 10 antibody, Cox10 antibody, cytochrome c oxidase assembly protein 10 antibody, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor antibody, COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog antibody, COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor antibody, cytochrome c oxidase 10 antibody, protoheme IX farnesyltransferase, mitochondrial antibody, Cox10 antibody, cox10 antibody, cox10.L antibody, COX10 antibody, LOC100732273 antibody
- 背景
- Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.
- 分子量
- 48910
- 基因ID
- 1352
- NCBI登录号
- NP_001294
- UniProt
- Q12887
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