This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MCHR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human MCHR1.
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.