CD11b 抗体 (N-Term)
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- 抗原 See all CD11b (ITGAM) 抗体
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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抗原表位
- AA 253-282, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD11b antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b.
- 克隆位点
- RB17991
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ITGAM Primary Antibody
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- 应用备注
- WB: 1:2000. WB: 1:1000. WB: 1:500. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart." in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013) (PubMed).
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Repetitive myocardial ischemia promotes coronary growth in the adult mammalian heart." in: Journal of the American Heart Association, Vol. 2, Issue 5, pp. e000343, (2013) (PubMed).
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- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- CD11b (ITGAM 产品)
- 背景
- CD11b is the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.
- 分子量
- 127179
- 基因ID
- 3684
- NCBI登录号
- NP_000623, NP_001139280
- UniProt
- P11215
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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