This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This NOS1AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-466 amino acids from the Central region of human NOS1AP.
MGC78853 antibody, Capon antibody, MGC145362 antibody, 6330408P19Rik antibody, CAPON antibody, nitric oxide synthase 1 adaptor protein antibody, nitric oxide synthase 1 adaptor protein L homeolog antibody, nitric oxide synthase 1 (neuronal) adaptor protein a antibody, carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein antibody, chromosome 18 C1orf226 homolog antibody, nitric oxide synthase 1 (neuronal) adaptor protein antibody, NOS1AP antibody, nos1ap.L antibody, nos1apa antibody, LOC609484 antibody, nos1ap antibody, LOC100058633 antibody, C18H1orf226 antibody, Nos1ap antibody
背景
This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.