Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
Pig
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED.
BLOS5 antibody, MU antibody, MUTED antibody, muted antibody, 1810074A19Rik antibody, Muted antibody, mu antibody, biogenesis of lysosomal organelles complex 1 subunit 5 antibody, biogenesis of lysosomal organelles complex 1 subunit 5 L homeolog antibody, biogenesis of lysosomal organelles complex-1, subunit 5, muted antibody, BLOC1S5 antibody, bloc1s5.L antibody, Bloc1s5 antibody
背景
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.