This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-291 amino acids from the Central region of human RGR.
RP44 antibody, MGC84794 antibody, RGR antibody, rgr antibody, zgc:110660 antibody, rgr2 antibody, wu:fb64c10 antibody, zgc:109930 antibody, retinal G protein coupled receptor antibody, retinal G protein coupled receptor L homeolog antibody, retinal G protein coupled receptor a antibody, retinal G protein coupled receptor b antibody, RGR antibody, Rgr antibody, rgr.L antibody, rgr antibody, rgra antibody, rgrb antibody
背景
This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).