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MARCO 抗体 (AA 13-40)

MARCO 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24662 unconjugated
产品编号 ABIN653847
发货至: 中国
  • 抗原 See all MARCO 抗体
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    抗原表位
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 13-40
    适用
    • 16
    • 5
    • 3
    • 2
    • 1
    • 1
    宿主
    • 13
    • 4
    • 1
    • 1
    克隆类型
    • 12
    • 6
    • 1
    多克隆
    标记
    • 18
    • 1
    This MARCO antibody is un-conjugated
    应用范围
    • 17
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MARCO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids of human MARCO.
    克隆位点
    RB24662
    亚型
    IgG
    Top Product
    Discover our top product MARCO Primary Antibody
  • 应用备注
    WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Ohta, Moriyama, Maehara, Gion, Furukawa, Tanaka, Hayashida, Yamauchi, Ishiguro, Mikami, Tsuboi, Iizuka-Koga, Kawano, Sato, Kiyoshima, Sumida, Nakamura: "DNA Microarray Analysis of Submandibular Glands in IgG4-Related Disease Indicates a Role for MARCO and Other Innate Immune-Related Proteins." in: Medicine, Vol. 95, Issue 7, pp. e2853, (2016) (PubMed).

    Chao, Makale, Karmali, Sharikov, Tsigelny, Merkulov, Kesari, Wrasidlo, Ruoslahti, Simberg: "Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains." in: Bioconjugate chemistry, Vol. 23, Issue 5, pp. 1003-9, (2014) (PubMed).

  • 抗原
    MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
    别名
    MARCO (MARCO 产品)
    背景
    MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
    分子量
    52658
    基因ID
    8685
    NCBI登录号
    NP_006761
    UniProt
    Q9UEW3
    途径
    Activation of Innate immune Response
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