This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ADCY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-441 amino acids from the Central region of human ADCY4.
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.