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WASP 抗体 (AA 116-144)

Name: WASP 抗体 (AA 116-144)
SKU: ABIN653830
Availability: OutOfStock

WAS 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23643 unconjugated

Western blot analysis of WAS Antibody (Center) (ABIN653830 and ABIN2843097) in mouse liver tissue lysates (35 μg/lane). (WASP 抗体 (AA 116-144))

WAS Antibody (Center) (ABIN653830 and ABIN2843097) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram). (WASP 抗体 (AA 116-144))

FACS

WAS Antibody (Center) (ABIN653830 and ABIN2843097) IHC analysis in formalin fixed and paraffin embedded tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (WASP 抗体 (AA 116-144))

IHC (p)

3 images

产品编号 ABIN653830

发货至: 中国

Datasheet as PDF

抗原 See all WASP (WAS) 抗体

WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
抗原表位
15

14

8

7

7

7

6

6

5

5

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 116-144
适用
87

55

19

2

1

1

1
人, 小鼠
宿主
84

3

1
兔
Compatible Secondaries
克隆类型
85

3
多克隆
标记
34

8

6

5

3

3

3

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1
This WASP antibody is un-conjugated
应用范围
62

39

27

15

13

13

8

5

5

4

4

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human WAS.

克隆位点

RB23643

亚型

Ig Fraction

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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 129-156), (C-Term) antibody
WAS 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 60-250) antibody
WAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 122-152), (Middle Region) antibody
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anti-Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS) (AA 101-200) antibody
WAS 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

别名

WAS (WAS 产品)

别名

IMD2 antibody, SCNX antibody, THC antibody, THC1 antibody, WASP antibody, U42471 antibody, WASp antibody, Wasp antibody, imd2 antibody, thc antibody, thc1 antibody, was antibody, wasp antibody, wu:fk81c08 antibody, zgc:64164 antibody, Wiskott-Aldrich syndrome antibody, neural Wiskott-Aldrich syndrome protein antibody, wiskott-aldrich syndrome protein antibody, Wiskott-Aldrich syndrome L homeolog antibody, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antibody, WAS antibody, LOC5578888 antibody, CpipJ_CPIJ006699 antibody, Was antibody, was.L antibody, wasb antibody

背景

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients.

分子量

52913

基因ID

7454

NCBI登录号

NP_000368

UniProt

P42768