This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TIFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from the N-terminal region of human TIFA.
TIFA antibody, xtifa antibody, T2BP antibody, T6BP antibody, TIFAA antibody, T2bp antibody, Ab2-389 antibody, TRAF interacting protein with forkhead associated domain antibody, TRAF-interacting protein with forkhead-associated domain antibody, TRAF-interacting protein with forkhead-associated domain S homeolog antibody, TIFA antibody, tifa antibody, Tifa antibody, tifa.S antibody
背景
Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.