This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.
GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).