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SRC8 抗体 (N-Term)

SRC8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24340 unconjugated
产品编号 ABIN653194
发货至: 中国
  • 抗原 See all SRC8 products
    SRC8 (SRC8 Protein (SRC8))
    抗原表位
    AA 9-38, N-Term
    适用
    宿主
    • 6
    克隆类型
    • 6
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SRC8 antibody is un-conjugated
    应用范围
    • 6
    • 6
    • 6
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    C, M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SRC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SRC8.
    克隆位点
    RB24340
    亚型
    Ig Fraction
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SRC8 (SRC8 Protein (SRC8))
    别名
    SRC8 (SRC8 产品)
    背景
    SRC8 is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.
    分子量
    61586
    基因ID
    2017
    NCBI登录号
    NP_001171669, NP_005222, NP_612632
    UniProt
    Q14247
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