This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This DEK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human DEK.
D6S231E antibody, DEK antibody, 1810019E15Rik antibody, D13H6S231E antibody, DEK proto-oncogene antibody, DEK proto-oncogene L homeolog antibody, DEK oncogene (DNA binding) antibody, DEK oncogene antibody, DEK antibody, Dek antibody, dek.L antibody, LOC398543 antibody
背景
DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases.