This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PEX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-370 amino acids from the C-terminal region of human PEX14.
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791] and Zellweger syndrome (ZWS) [MIM:214100].