SFRP1 抗体 (N-Term)
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- 抗原 See all SFRP1 抗体
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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抗原表位
- AA 26-55, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SFRP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.
- 克隆位点
- RB21557
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SFRP1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).
: "Expression and prognostic value of SFRP1 and β-catenin in patients with glioblastoma." in: Oncology letters, Vol. 11, Issue 1, pp. 69-74, (2016) (PubMed).
: "Deregulation of secreted frizzled-related proteins is associated with aberrant β-catenin activation in the carcinogenesis of oral submucous fibrosis." in: OncoTargets and therapy, Vol. 8, pp. 2923-31, (2015) (PubMed).
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Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).
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- 抗原
- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
- 别名
- SFRP1 (SFRP1 产品)
- 别名
- FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP2 antibody, 2210415K03Rik antibody, AW011917 antibody, AW107218 antibody, AW742929 antibody, sFRP-1 antibody, CSFRP1 antibody, SFRP1 antibody, XfrzA antibody, frp antibody, frp-1 antibody, frp1 antibody, frzA antibody, sarp2 antibody, sfrp1 antibody, LOC100231868 antibody, Srfp1a antibody, wu:fd19b09 antibody, secreted frizzled related protein 1 antibody, secreted frizzled-related protein 1 antibody, Secreted frizzled-related protein 1 antibody, secreted frizzled-related protein 1a antibody, secreted frizzled-related protein 1b antibody, SFRP1 antibody, Sfrp1 antibody, sfrp1 antibody, sfrp1a antibody, sfrp1b antibody
- 背景
- SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer.
- 分子量
- 35386
- 基因ID
- 6422
- NCBI登录号
- NP_003003
- UniProt
- Q8N474
- 途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
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