LMX1B 抗体 (AA 175-202)
(2 references)-
- 抗原 See all LMX1B 抗体
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
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抗原表位
- AA 175-202
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LMX1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- C, X
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This LMX1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the Central region of human LMX1B.
- 克隆位点
- RB21468
- 亚型
- Ig Fraction
- Top Product
- Discover our top product LMX1B Primary Antibody
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anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-110) antibody
LMX1B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (Internal Region) antibodyLMX1B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-110) antibodyLMX1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 324-373) antibodyLMX1B 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 斑马鱼, 豚鼠, 兔, 小鸡, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (Internal Region) antibodyVerified LMX1B 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 1-100) antibodyLMX1B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Homeobox Transcription Factor 1, beta (LMX1B) (AA 136-395) antibodyLMX1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 30, pp. E4387-96, (2018) (PubMed).
: "Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease." in: Nature neuroscience, Vol. 18, Issue 6, pp. 826-35, (2015) (PubMed).
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: "Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 30, pp. E4387-96, (2018) (PubMed).
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- 抗原
- LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))
- 别名
- LMX1B (LMX1B 产品)
- 别名
- LMX1.2 antibody, NPS1 antibody, LMX antibody, LMX1 antibody, LMX1.1 antibody, lmx1b antibody, lmx1b.1 antibody, Xlmx1b antibody, lmx1b.2 antibody, LIM homeobox transcription factor 1 beta antibody, LIM homeobox transcription factor 1, beta b antibody, LIM homeobox transcription factor 1, beta, gene 1 S homeolog antibody, LIM homeobox transcription factor 1, beta a antibody, LMX1B antibody, Lmx1b antibody, lmx1bb antibody, lmx1b.1.S antibody, lmx1ba antibody
- 背景
- LMX1B is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.
- 分子量
- 44917
- 基因ID
- 4010
- NCBI登录号
- NP_001167618, NP_002307
- UniProt
- O60663
- 途径
- Dopaminergic Neurogenesis
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