This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This PISD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-250 amino acids from the Central region of human PISD.
Phosphatidylserine decarboxylases catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits