Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ITGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1.
ITGA1
适用: 人
IHC, ELISA, IF
宿主: 兔
Polyclonal
unconjugated
应用备注
WB: 1:1000. IHC-P: 1:10~50
限制
仅限研究用
状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
Gutiérrez-Franco, Costa, Eixarch, Castillo, Medina-Rodríguez, Bribián, de Castro, Montalban, Espejo: "Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design." in: Clinical immunology (Orlando, Fla.), Vol. 163, pp. 22-33, (2016) (PubMed).
ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.