This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human XPA.
CG6358 antibody, DhR14 antibody, DhXPA antibody, DmXPA antibody, Dmel\\CG6358 antibody, Dxpa antibody, EG:EG0007.8 antibody, XPAC antibody, XPA_DROME antibody, Xpa antibody, dmXPA antibody, dxpa antibody, XP1 antibody, AI573865 antibody, Xpac antibody, xpac antibody, xxpa antibody, Xeroderma pigmentosum group A-like antibody, XPA, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group A antibody, xeroderma pigmentosum, complementation group A L homeolog antibody, Xpac antibody, XPA antibody, Xpa antibody, xpa.L antibody
背景
XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.