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PHD1 抗体 (AA 194-221)
EGLN2
适用: 人
WB, FACS, IHC (p)
宿主: 兔
Polyclonal
RB22708
unconjugated
PHD1抗体详情
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抗原
See all PHD1 (EGLN2) 抗体
PHD1 (EGLN2)
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
抗原表位
All epitopes for PHD1 抗体
AA 194-221
适用
All reactivities for PHD1 抗体
人
宿主
All hosts for PHD1 抗体
兔
克隆类型
All clonalities for PHD1 抗体
多克隆
标记
All conjugates for PHD1 抗体
This PHD1 antibody is un-conjugated
应用范围
All applications for PHD1 抗体
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This EGLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-221 amino acids from the Central region of human EGLN2.
克隆位点
RB22708
亚型
Ig Fraction
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Discover our top product EGLN2 Primary Antibody
Alternatives
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anti-Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2) (AA 281-315) antibody
EGLN2
适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, Pig, 猴, Bat
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
PHD1目标详情
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抗原
PHD1 (EGLN2)
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
别名
EGLN2 (EGLN2 产品 )
别名
egln2 antibody, phd2 antibody, PHD1 antibody, 0610011A13Rik antibody, C85656 antibody, Hif-p4h-1 antibody, Ier4 antibody, Phd1 antibody, SM-20 antibody, HIF-PH1 antibody, HPH-1 antibody, HPH-3 antibody, PHD-1 antibody, EIT6 antibody, HIFPH1 antibody, egl-9 family hypoxia-inducible factor 1 antibody, egl-9 family hypoxia inducible factor 2 antibody, Egl nine homolog 2 antibody, egl-9 family hypoxia-inducible factor 2 L homeolog antibody, egl-9 family hypoxia-inducible factor 2 antibody, egln1 antibody, EGLN2 antibody, egln2 antibody, egln2.L antibody, Egln2 antibody
背景
EGLN2 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. It functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation.
分子量
43650
基因ID
112398
NCBI登录号
NP_444274 , NP_542770
UniProt
Q96KS0
途径
Intracellular Steroid Hormone Receptor Signaling Pathway , Cell RedoxHomeostasis
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