Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
B, C, M, Pig
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SFRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-38 amino acids from the N-terminal region of human SFRS1.
SFRS1 is a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins.