ARHGEF3 抗体 (AA 211-240)
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- 抗原 See all ARHGEF3 抗体
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
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抗原表位
- AA 211-240
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARHGEF3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.
- 克隆位点
- RB27451
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ARHGEF3 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).
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- 抗原
- ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
- 别名
- ARHGEF3 (ARHGEF3 产品)
- 别名
- MGC82822 antibody, ARHGEF3 antibody, si:ch211-258l4.8 antibody, MGC108040 antibody, DKFZp459N027 antibody, GEF3 antibody, STA3 antibody, XPLN antibody, 1200004I24Rik antibody, 9830169H03Rik antibody, C76747 antibody, Xpln antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antibody, Rho guanine nucleotide exchange factor 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antibody, arhgef3.1.S antibody, ARHGEF3 antibody, arhgef3 antibody, arhgef3.1 antibody, Arhgef3 antibody
- 背景
- Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 59783
- 基因ID
- 50650
- NCBI登录号
- NP_001122087, NP_001122088, NP_062455
- UniProt
- Q9NR81
- 途径
- Neurotrophin Signaling Pathway
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