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AXIN2 抗体 (C-Term)

AXIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26798 unconjugated
产品编号 ABIN2840323
发货至: 中国
  • 抗原 See all AXIN2 抗体
    AXIN2 (Axin 2 (AXIN2))
    抗原表位
    • 15
    • 14
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 816-843, C-Term
    适用
    • 71
    • 53
    • 40
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 84
    • 2
    克隆类型
    • 75
    • 11
    多克隆
    标记
    • 25
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AXIN2 antibody is un-conjugated
    应用范围
    • 63
    • 38
    • 30
    • 14
    • 13
    • 13
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M, Rat
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This AXIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2.
    克隆位点
    RB26798
    亚型
    Ig Fraction
    Top Product
    Discover our top product AXIN2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    AXIN2 (Axin 2 (AXIN2))
    别名
    AXIN2 (AXIN2 产品)
    别名
    AXIL antibody, ODCRCS antibody, axil antibody, wu:fb37c08 antibody, zgc:111942 antibody, axin-2 antibody, xarp antibody, MGC81576 antibody, arp-A antibody, axin2 antibody, Axi1 antibody, Axil antibody, Conductin antibody, axin 2 antibody, axin 2 (conductin, axil) antibody, axin 2 (conductin, axil) S homeolog antibody, AXIN2 antibody, axin2 antibody, axin2.S antibody, Axin2 antibody
    背景
    The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
    分子量
    93558
    基因ID
    8313
    NCBI登录号
    NP_004646
    UniProt
    Q9Y2T1
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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