This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.
TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.