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LCK 抗体 (C-Term)

LCK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17753 unconjugated
产品编号 ABIN650741
发货至: 中国
  • 抗原 See all LCK 抗体
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    抗原表位
    • 28
    • 16
    • 16
    • 11
    • 10
    • 8
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    AA 480-509, C-Term
    适用
    • 173
    • 98
    • 64
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
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    • 1
    宿主
    • 157
    • 14
    • 2
    克隆类型
    • 159
    • 15
    多克隆
    标记
    • 99
    • 10
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    This LCK antibody is un-conjugated
    应用范围
    • 132
    • 94
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    • 23
    • 16
    • 14
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    • 9
    • 3
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This LCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human LCK.
    克隆位点
    RB17753
    亚型
    Ig Fraction
    Top Product
    Discover our top product LCK Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
    别名
    LCK (LCK 产品)
    别名
    zgc:136695 antibody, LCK antibody, Hck-3 antibody, Lsk antibody, Lskt antibody, p56 antibody, p56Lck antibody, LSK antibody, YT16 antibody, p56lck antibody, pp58lck antibody, P56LCK antibody, tkl antibody, Lck1 antibody, Lcktkr antibody, LCK proto-oncogene, Src family tyrosine kinase antibody, lymphocyte protein tyrosine kinase antibody, lck antibody, LCK antibody, Lck antibody
    背景
    LCK is a member of the Src family of protein tyrosine kinases (PTKs). This protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
    分子量
    58001
    基因ID
    3932
    NCBI登录号
    NP_001036236, NP_005347
    UniProt
    P06239
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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