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MBP 抗体 (AA 177-209)

适用: 人 WB 宿主: 兔 Polyclonal RB15523 unconjugated
产品编号 ABIN650720
发货至: 中国
  • 抗原 See all MBP products
    MBP
    抗原表位
    • 22
    • 16
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 177-209
    适用
    • 66
    • 47
    • 44
    • 4
    • 3
    宿主
    • 59
    • 10
    • 2
    • 1
    克隆类型
    • 58
    • 14
    多克隆
    标记
    • 24
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBP antibody is un-conjugated
    应用范围
    • 35
    • 29
    • 26
    • 26
    • 23
    • 10
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This MBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-209 amino acids from human MBP.
    克隆位点
    RB15523
    亚型
    IgG
  • 应用备注
    WB: 1:16000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    MBP
    Abstract
    MBP 产品
    别名
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, myelin basic protein antibody, myelin basic protein a antibody, MBP antibody, Mbp antibody, mbpa antibody
    背景
    MBP is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called Golli-MBP) that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.
    分子量
    33117
    基因ID
    4155
    NCBI登录号
    NP_001020252, NP_001020261, NP_001020263, NP_001020271, NP_001020272, NP_002376
    UniProt
    P02686
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