Vimentin 抗体 (Biotin)
-
- 抗原 See all Vimentin (VIM) 抗体
- Vimentin (VIM)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Vimentin antibody is conjugated to Biotin
-
应用范围
- Immunohistochemistry (IHC)
- 原理
- Mouse Anti-Human Vimentin, Biotinylated
- 交叉反应 (详细)
- Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
- 产品特性
- Collagen & Extracellular Matrix Proteins
- 免疫原
- Purified Human Vimentin.
- 亚型
- IgG1
- Top Product
- Discover our top product VIM Primary Antibody
-
-
- 应用备注
- Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
- 浓度
- 1 mg/ml in PBS (after reconstitution).
- 储存条件
- -20 °C
- 储存方法
- -20°C
-
- 抗原
- Vimentin (VIM)
- 别名
- Vimentin (VIM 产品)
- 背景
-
Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
- 途径
- Caspase Cascade in Apoptosis
-