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Vimentin 抗体 (Biotin)

VIM 适用: 人 IHC 宿主: 小鼠 Monoclonal Biotin
产品编号 ABIN645827
发货至: 中国
  • 抗原 See all Vimentin (VIM) 抗体
    Vimentin (VIM)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Vimentin antibody is conjugated to Biotin
    应用范围
    • 263
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    Immunohistochemistry (IHC)
    原理
    Mouse Anti-Human Vimentin, Biotinylated
    交叉反应 (详细)
    Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    产品特性
    Collagen & Extracellular Matrix Proteins
    免疫原
    Purified Human Vimentin.
    亚型
    IgG1
    Top Product
    Discover our top product VIM Primary Antibody
  • 应用备注
    Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
    浓度
    1 mg/ml in PBS (after reconstitution).
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    Vimentin (VIM)
    别名
    Vimentin (VIM 产品)
    背景

    Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

    途径
    Caspase Cascade in Apoptosis
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