Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This product recognizes an epitope within the C-terminal region (CT) of the 244 amino acid protein Adiponectin (also known as Acrp30), a major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, Adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of Adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis.
交叉反应
人, 小鼠, 大鼠
产品特性
Rabbit Anti-Adiponectin (C-terminus)
纯化方法
Purified
免疫原
A 15 amino acid peptide located near human Adiponectin carboxy-terminus.