S100A8 抗体 (AA 30-110)
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- 抗原 See all S100A8 抗体
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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抗原表位
- AA 30-110
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S100A8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Unconjugated Rabbit polyclonal to S10A8
- 特异性
- S10A8 Polyclonal Antibody detects endogenous levels of protein.
- 纯化方法
- S10A8 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human S10A8 protein.
- 亚型
- IgG
- Top Product
- Discover our top product S100A8 Primary Antibody
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- 应用备注
- WB 1:500-2000 ELISA 1:5000-20000
- 说明
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Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid form in PBS containing 50 % glycerol,and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- 别名
- S10A8 (S100A8 产品)
- 别名
- 60B8AG antibody, CAGA antibody, CFAG antibody, CGLA antibody, CP-10 antibody, L1Ag antibody, MA387 antibody, MIF antibody, MRP8 antibody, NIF antibody, P8 antibody, Mrp8 antibody, S100A8 antibody, 60B8Ag antibody, AI323541 antibody, B8Ag antibody, CFAg antibody, Caga antibody, p8 antibody, MRP-8 antibody, S100 calcium binding protein A8 antibody, S100 calcium binding protein A8 (calgranulin A) antibody, S100A8 antibody, S100a8 antibody
- 分子量
- 10 kDa
- 基因ID
- 6279
- UniProt
- P05109
- 途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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