LAMP1 抗体
(9 references)-
- 抗原 See all LAMP1 抗体
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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适用
- 人, 小鼠, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAMP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- The mouse monoclonal antibody H4A3 recognizes an extracellular/luminal epitope of CD107a, an approximately 100-120 kDa glycoprotein expressed mainly on lysosomal, but also on the plasma membrane.
- 交叉反应 （详细）
- Human, Non-Human Primates, Mouse
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Human PBMC
- 克隆位点
- H4A3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product LAMP1 Primary Antibody
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 80-280) antibody
LAMP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibodyLAMP1 适用: 人, 小鼠, 大鼠, 猴 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 49-297) antibodyLAMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal Ly1C6 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154) antibodyLAMP1 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 人, 小鼠, 灵长类 WB, FACS, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)LAMP1 适用: 小鼠 WB, FACS, IHC, IP, IHC (p), IHC (fro) 宿主: 大鼠 Monoclonal FITC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (APC)LAMP1 适用: 人, 小鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal H4A3 APC
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibodyLAMP1 适用: 人, Green Monkey WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (Biotin)LAMP1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal H4A3 Biotin
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- 应用备注
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Western blotting: Recommended dilution: 1 μg/mL.
Immunohistochemistry: Recommended dilution: 2-8 μg/mL.
Flow cytometry: Intracellular and extracellular staining, recommended dilution: 1-12 μg/mL. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "Danon disease: a focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency." in: Gene, Vol. 498, Issue 2, pp. 183-95, (2012) (PubMed).
: "Inhibition of human natural killer cell activity by influenza virions and hemagglutinin." in: Journal of virology, Vol. 84, Issue 9, pp. 4148-57, (2010) (PubMed).
: "Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines." in: Blood, Vol. 112, Issue 9, pp. 3671-8, (2008) (PubMed).
: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." in: Cancer research, Vol. 67, Issue 3, pp. 1317-25, (2007) (PubMed).
: "NK cell lysis of HIV-1-infected autologous CD4 primary T cells: requirement for IFN-mediated NK activation by plasmacytoid dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 4, pp. 2097-104, (2007) (PubMed).
: "Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease." in: Blood, Vol. 108, Issue 7, pp. 2316-23, (2006) (PubMed).
: "Gamma interferon secretion by human Vgamma2Vdelta2 T cells after stimulation with antibody against the T-cell receptor plus the Toll-Like receptor 2 agonist Pam3Cys." in: Infection and immunity, Vol. 74, Issue 8, pp. 4505-11, (2006) (PubMed).
: "Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases." in: The American journal of pathology, Vol. 159, Issue 2, pp. 449-55, (2001) (PubMed).
: "Purification and characterization of human lysosomal membrane glycoproteins." in: Archives of biochemistry and biophysics, Vol. 268, Issue 1, pp. 360-78, (1989) (PubMed).
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: "Danon disease: a focus on processing of the novel LAMP2 mutation and comments on the beneficial use of peripheral white blood cells in the diagnosis of LAMP2 deficiency." in: Gene, Vol. 498, Issue 2, pp. 183-95, (2012) (PubMed).
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- 抗原
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- 别名
- CD107a (LAMP1 产品)
- 别名
- CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
- 背景
- Lysosomal associated membrane protein 1,CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.,LAMP-1, LAMPA
- 基因ID
- 3916
- UniProt
- P11279
- 途径
- Autophagy
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