(1 reference)-
- 抗原 See all Dinitrophenol (DNP) products
- Dinitrophenol (DNP)
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Dinitrophenol antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 免疫原
- Dinitrophenol antibody was raised in goat using dinitrophenol-modified protein as the immunogen.
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- 应用备注
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ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Supplied as liquid whole serum without preservative
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).
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: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." in: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).
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- 抗原
- Dinitrophenol (DNP)
- 别名
- DNP (DNP 产品)
- 物质类
- Chemical
- 背景
- Tissues are continually exposed to reactive oxygen species (ROS) that are produced in tissues from metabolism processes or the inflammatory response of leukocytes or macrophages. It is estimated that as much as 1 % of consumed oxygen may be converted to ROS, which can cause damage to various cellular components. Proteins are one of the cellular components most vulnerable to oxidative damage by ROS, which results in an increase in protein carbonyl content. This oxidative modification of proteins can lead to cross-linking, peptide fragmentation, modified residues and the conversion of one amino group to another. If sufficient protein damage accumulates, cell death will occur.
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