Optimal conditions should be determined byt he investigator.
限制
仅限研究用
状态
Lyophilized
浓度
Lot specific
缓冲液
Lyophilized from PBS, pH 7.2.
注意事项
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
储存条件
4 °C/-20 °C
储存方法
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
CD-RAP antibody, Mia1 antibody, Cdrap antibody, zgc:194157 antibody, mia antibody, CDRAP antibody, Fdp antibody, MIA antibody, MIAL antibody, melanoma inhibitory activity antibody, otoraplin antibody, cilia and flagella associated protein 100 antibody, MIA antibody, Mia antibody, mia antibody, Otor antibody, CFAP100 antibody
背景
MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family, MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.