Presenilin 2 抗体
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- 抗原 See all Presenilin 2 (PSEN2) 抗体
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
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适用
- 哺乳动物
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Presenilin 2 antibody is un-conjugated
- 应用范围
- 请咨询
- 纯化方法
- Purified
- Top Product
- Discover our top product PSEN2 Primary Antibody
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- 应用备注
- Optimal conditions should be determined byt he investigator.
- 限制
- 仅限研究用
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- 浓度
- Lot specific
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- 抗原
- Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))
- 别名
- Presenilin 2 (PSEN2 产品)
- 背景
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.
- 途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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