ANKRA1 antibody, BLS antibody, F14150_1 antibody, RFX-B antibody, Tvl1 antibody, regulatory factor X associated ankyrin containing protein antibody, regulatory factor X-associated ankyrin-containing protein antibody, RFXANK antibody, Rfxank antibody
背景
RFX-B is the gene responsible for the bare lymphocyte syndrome (BLS) which is characterized by a lack of MHC class II transcription. Subsequently, there is a lack of B and T cell responses to foreign antigens. RFX-B is a MHC class II transcription factor that is defective in BLS.