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TMEM123 抗体 (C-Term)

TMEM123 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN635901
发货至: 中国
  • 抗原 See all TMEM123 抗体
    TMEM123 (Transmembrane Protein 123 (TMEM123))
    抗原表位
    • 16
    • 3
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    • 1
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    C-Term
    适用
    • 34
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    宿主
    • 31
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    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 10
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    This TMEM123 antibody is un-conjugated
    应用范围
    • 28
    • 17
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    Western Blotting (WB)
    特异性
    TMEM123 antibody was raised against the C terminal of TMEM123
    纯化方法
    Affinity purified
    免疫原
    TMEM123 antibody was raised using the C terminal of TMEM123 corresponding to a region with amino acids SSVTITTTMHSEAKKGSKFDTGSFVGGIVLTLGVLSILYIGCKMYYSRRG
    Top Product
    Discover our top product TMEM123 Primary Antibody
  • 应用备注
    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    TMEM123 Blocking Peptide, catalog no. 33R-8860, is also available for use as a blocking control in assays to test for specificity of this TMEM123 antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMEM123 antibody in PBS
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • 抗原
    TMEM123 (Transmembrane Protein 123 (TMEM123))
    别名
    TMEM123 (TMEM123 产品)
    别名
    KCT3 antibody, PORIMIN antibody, PORMIN antibody, 2310075C12Rik antibody, RGD1305625 antibody, kct3 antibody, pormin antibody, porimin antibody, transmembrane protein 123 antibody, transmembrane protein 123 L homeolog antibody, TMEM123 antibody, Tmem123 antibody, tmem123.L antibody, tmem123 antibody
    背景
    TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.
    分子量
    19 kDa (MW of target protein)
    途径
    Regulation of Cell Size
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