INSIG1 抗体 (Middle Region)
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- 抗原 See all INSIG1 抗体
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INSIG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- INSIG1 antibody was raised against the middle region of INSIG1
- 纯化方法
- Affinity purified
- 免疫原
- INSIG1 antibody was raised using the middle region of INSIG1 corresponding to a region with amino acids WWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINH
- Top Product
- Discover our top product INSIG1 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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INSIG1 Blocking Peptide, catalog no. 33R-10042, is also available for use as a blocking control in assays to test for specificity of this INSIG1 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of INSIG1 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- INSIG1 (Insulin Induced Gene 1 (INSIG1))
- 别名
- INSIG1 (INSIG1 产品)
- 别名
- cl-6 antibody, cl6 antibody, CL-6 antibody, CL6 antibody, fb55a03 antibody, fi35b10 antibody, wu:fb55a03 antibody, wu:fi35b10 antibody, zgc:55439 antibody, 1810013C12Rik antibody, Insig-1 antibody, INSIG-1 antibody, insulin induced gene 1 antibody, insulin induced gene 1 L homeolog antibody, INSIG1 antibody, insig1 antibody, insig1.L antibody, Insig1 antibody
- 背景
- Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.
- 分子量
- 25 kDa (MW of target protein)
- 途径
- ER-Nucleus Signaling
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