GADD45B 抗体 (Middle Region)
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- 抗原 See all GADD45B 抗体
- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GADD45B antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- GADD45 B antibody was raised against the middle region of GADD45
- 纯化方法
- Affinity purified
- 免疫原
- GADD45 B antibody was raised using the middle region of GADD45 corresponding to a region with amino acids FCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAW
- Top Product
- Discover our top product GADD45B Primary Antibody
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- 应用备注
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WB: 0.25 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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GADD45B Blocking Peptide, catalog no. 33R-2851, is also available for use as a blocking control in assays to test for specificity of this GADD45B antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GADD40 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
- 别名
- GADD45B (GADD45B 产品)
- 别名
- GADD45BETA antibody, MYD118 antibody, AI323528 antibody, Myd118 antibody, CS131 antibody, cb196 antibody, gadd45b antibody, gadd45b2 antibody, sb:cb196 antibody, zgc:73104 antibody, gadd45beta antibody, wu:fa92d10 antibody, wu:fa98h12 antibody, wu:fk65h03 antibody, zgc:111973 antibody, gadd45b1 antibody, gadd45bl antibody, zgc:112453 antibody, growth arrest and DNA damage inducible beta antibody, growth arrest and DNA-damage-inducible 45 beta antibody, growth arrest and DNA-damage-inducible, beta antibody, growth arrest and DNA-damage-inducible, beta a antibody, growth arrest and DNA-damage-inducible, beta b antibody, GADD45B antibody, Gadd45b antibody, gadd45ba antibody, gadd45bb antibody
- 背景
- GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
- 分子量
- 18 kDa (MW of target protein)
- 途径
- Cell Division Cycle
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