IL-15 抗体 (N-Term)
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- 抗原 See all IL-15 (IL15) 抗体
- IL-15 (IL15) (Interleukin 15 (IL15))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL-15 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- IL15 antibody was raised against the N terminal of IL15
- 纯化方法
- Affinity purified
- 免疫原
- IL15 antibody was raised using the N terminal of IL15 corresponding to a region with amino acids RISKPHLRSISIQCYLCLLLNSHFLTEAGIHVFILGCFSAGLPKTEANWV
- Top Product
- Discover our top product IL15 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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IL15 Blocking Peptide, catalog no. 33R-7982, is also available for use as a blocking control in assays to test for specificity of this IL15 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IL15 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- IL-15 (IL15) (Interleukin 15 (IL15))
- 别名
- IL15 (IL15 产品)
- 别名
- IL15 antibody, AI503618 antibody, IL-15 antibody, interleukin 15 antibody, IL15 antibody, Il15 antibody
- 背景
- IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
- 分子量
- 13 kDa (MW of target protein)
- 途径
- JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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