IREB2 抗体 (Middle Region)
-
- 抗原 See all IREB2 抗体
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
-
抗原表位
- Middle Region
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This IREB2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- IREB2 antibody was raised against the middle region of IREB2
- 纯化方法
- Affinity purified
- 免疫原
- IREB2 antibody was raised using the middle region of IREB2 corresponding to a region with amino acids IQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEK
- Top Product
- Discover our top product IREB2 Primary Antibody
-
-
- 应用备注
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
-
IREB2 Blocking Peptide, catalog no. 33R-4113, is also available for use as a blocking control in assays to test for specificity of this IREB2 antibody
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of IREB2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
- 抗原
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- 别名
- IREB2 (IREB2 产品)
- 别名
- IREB2 antibody, im:7153062 antibody, DKFZp468N047 antibody, D9Ertd85e antibody, Irp2 antibody, ACO3 antibody, IRP2 antibody, IRP2AD antibody, IREBP2 antibody, iron responsive element binding protein 2 antibody, iron-responsive element binding protein 2 antibody, iron responsive element binding protein 2 L homeolog antibody, IREB2 antibody, ireb2 antibody, Ireb2 antibody, ireb2.L antibody
- 背景
- IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
- 分子量
- 105 kDa (MW of target protein)
- 途径
- Transition Metal Ion Homeostasis
-