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- 抗原 See all CPSF4 抗体
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPSF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- CPSF4 antibody was raised against the C terminal of CPSF4
- 纯化方法
- Affinity purified
- 免疫原
- CPSF4 antibody was raised using the C terminal of CPSF4 corresponding to a region with amino acids SLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEK
- Top Product
- Discover our top product CPSF4 Primary Antibody
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anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-244) antibody
CPSF4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 81-180) antibodyCPSF4 适用: 人, 小鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) antibodyCPSF4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 1-243) antibodyCPSF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (C-Term) antibodyCPSF4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4) (AA 31-216) antibodyCPSF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 0.5 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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CPSF4 Blocking Peptide, catalog no. 33R-8599, is also available for use as a blocking control in assays to test for specificity of this CPSF4 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CPSF4 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- CPSF4 (Cleavage and Polyadenylation Specific Factor 4, 30kDa (CPSF4))
- 别名
- CPSF4 (CPSF4 产品)
- 别名
- cpsf30 antibody, nar antibody, neb1 antibody, 30kDa antibody, C79664 antibody, CPSF30 antibody, NAR antibody, NEB1 antibody, cleavage and polyadenylation specific factor 4 antibody, cleavage and polyadenylation specific factor 4, 30kDa antibody, cleavage and polyadenylation specific factor 4 S homeolog antibody, CPSF4 antibody, Cpsf4 antibody, LOC733099 antibody, LOC100360200 antibody, cpsf4.S antibody, cpsf4 antibody
- 背景
- Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30 kDa subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs.
- 分子量
- 24 kDa (MW of target protein)
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